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Toluene detection in the pharmaceutical industry

Toluene is an organic solvent widely used in the pharmaceutical industry for the synthesis of active ingredients, extraction of compounds and other laboratory operations. Despite its usefulness, toluene poses significant risks to human health and the environment, making its detection and monitoring in industrial processes crucial.

Toluene detection, why it is important

Exposure to toluene can cause a range of health problems:

  • Acute: Eye, nose and throat irritation, headaches, dizziness and confusion.
  • Chronic: Central nervous system damage, liver and kidney effects, and potential reproductive effects.

Inhalation of toluene vapor is the most common route of exposure, making monitoring of its presence in the air within work environments crucial.

Toluene detection: most common uses

Toluene has chemical and physical properties that make it suitable for a wide range of applications, including:

  • Chemical synthesis: it is used as a reagent or solvent in chemical synthesis reactions to produce various drugs and active pharmaceutical ingredients. It is essential in processes such as nitriding, chlorination and other organic reactions.
  • Benzaldehyde and phenol production: toluene is oxidized to obtain the chemicals used as intermediates in various syntheses.
  • Compound extract: used to extract active ingredients from plants and other natural materials because of its ability to dissolve a wide range of organic compounds.
  • Solvent for laboratory reactions: in chemical and pharmaceutical laboratories, toluene is frequently used as a solvent for a wide range of chemical reactions and for cleaning equipment.

The benefits of using toluene

Toluene has several characteristics that make its use advantageous:

  • It effectively dissolves many organic compounds, making it an ideal solvent for various industrial applications
  • It is widely available and relatively inexpensive, making it a very viable.
  • Toluene’s volatility and relatively low boiling point make it easy to remove from end products by evaporation.

Technologies used for the detection of toluene

A PID technology sensor can be used for the proper detection of toluene. Its lifetime depends on various factors, including the quality of the sensor itself, operating conditions and frequency of use. However, key elements, such as the UV lamp, have life cycles ranging from 6 to 12 months, necessitating maintenance for replacement. In addition, depending on the manufacturer’s instructions, periodic calibration of the detector will also be necessary to ensure accurate detection.

Discover our produtcs

Sensitron gas detectors are suitable for use in any application:

SMART 3G D2

Suitable for detecting the presence of flammable substances, toxic gases, refrigerants and oxygen in classified areas.ATEX, IECEx and SIL2/3 certified

SMART 3G D3

SMART 3G D3

Suitable for detecting in classified areas,ATEX, IECEx and SIL2/3 certified, enables non-intrusive field calibration.

SMART 3G C2

Suitable for detecting, in classified areas, the presence of flammable substances (% LFL), toxic gases in ppm, refrigerant gases or for the detection of oxygen deficiency or excess.

Our certifications

Within hazardous environments where strict safety standards must be met, it is important to use products that are certified and in line with regulations. Learn about our certifications:

ATEX

The Directive sets out the requirements and assessment of equipment intended for use in potentially explosive atmospheres.

IECEx

IECEx

The IECEx system is an international certification system. It is developed by the International Electrotechnical Commission.

certificazione SIL

SIL

The Safety Integrity Level (SIL) is the ability to reduce the assessed risk by ensuring the reliability of safety systems.

Explore in virtual reality

Within the Sensitron metaverse you can explore application realities reconstructed in virtual reality. Find out more about who we are and what we do, walk inside a production area, and learn more about gas hazards.

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IN 2025,
SENSITRON
COMPLIES 37 YEARS

We celebrated this achievement, with a new logo: in the handshake we see the commitment made with our customers, but also collaboration, the doing together the best we can without compromise.

Founded in 1988 in the province of Milan, Sensitron becomes part of the Halma plc group in 2021.